Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | RARG | P13631 | 3/20 | 0.47 |
| ▸ | RARA | P10276 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850145 | 0.89 | SSTR5 (0.46) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL8458446 | 0.87 | RARA (0.57) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL9850151 | 0.85 | MAPT (0.48) | RARBRARAKMT2APOLBACR | |
| SCHEMBL9850236 | 0.85 | RARB (0.45) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL5736766 | 0.84 | CYP26B1 (0.48) | RARBRARACYP26A1HIF1APRSS1 | |
| SCHEMBL9850206 | 0.83 | HIF1A (0.49) | RARBRARAKMT2AHIF1ALMNA | |
| SCHEMBL9850154 | 0.81 | RARB (0.67) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL5736859 | 0.80 | SSTR5 (0.38) | RARBRARAKMT2AHGFACCYP26A1 | |
| SCHEMBL9850280 | 0.80 | RXRA (0.41) | RARBRARGRARACYP3A4KMT2A | |
| SCHEMBL8759232 | 0.80 | RARB (0.47) | RARBRARGRARACYP3A4CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |