Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850280 | 0.93 | RXRA (0.41) | MAPTSMN1; SMN2MGLLRXRARARB | |
| SCHEMBL9850095 | 0.92 | RARA (0.47) | MAPTRXRARARBRARAPRSS1 | |
| SCHEMBL9850227 | 0.92 | RXRA (0.48) | RXRARARBRARATSHR | |
| SCHEMBL9850290 | 0.91 | MAPT (0.41) | MAPTSMN1; SMN2RXRARARBRARA | |
| SCHEMBL9850306 | 0.87 | HIF1A (0.41) | MAPTRXRARARBRARAPRSS1 | |
| SCHEMBL9850174 | 0.85 | RARB (0.48) | MAPTSMN1; SMN2MGLLRXRARARB | |
| SCHEMBL9850216 | 0.85 | RARA (0.49) | MAPTRXRARARBRARAPRSS1 | |
| SCHEMBL9850214 | 0.85 | RXRA (0.52) | RXRARARBRARARARG | |
| SCHEMBL9850094 | 0.84 | MAPT (0.43) | MAPTSMN1; SMN2RXRARARBRARA | |
| SCHEMBL9850236 | 0.83 | RARB (0.45) | MAPTSMN1; SMN2RARBRARAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |