SCHEMBL9850285

SCHEMBL9850285

[CH2]c1cccc(NC(=O)CCCCCCCCCCC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
POLB P06746 1/20 0.58
SOAT2 O75908 1/20 0.58
SOAT1 P35610 1/20 0.58
KDM4E B2RXH2 1/20 0.57
HDAC3 O15379 5/20 0.56
HDAC1 Q13547 5/20 0.56
HDAC2 Q92769 5/20 0.56
HDAC10 Q969S8 4/20 0.56
HDAC11 Q96DB2 4/20 0.56
HDAC8 Q9BY41 4/20 0.56
HDAC6 Q9UBN7 4/20 0.56
NCOR2 Q9Y618 1/20 0.56
EPHX2 P34913 1/20 0.55
HDAC4 P56524 3/20 0.55
HDAC7 Q8WUI4 3/20 0.55
HDAC9 Q9UKV0 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187158 1.00 LMNA (0.59) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL11901010 0.88 LMNA (0.69) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL11330626 0.84 LMNA (0.58) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL9115650 0.84 HDAC3 (0.78) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL21234556 0.84 HDAC4 (0.65) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL8741843 0.84 HDAC4 (0.65) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL11638630 0.84 LMNA (0.61) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL28732582 0.84 HDAC4 (0.65) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL8388528 0.84 HDAC4 (0.65) LMNANPC1RAB9ASMN1; SMN2POLB
SCHEMBL10969527 0.82 KDM4E (0.72) LMNANPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0418743-A2 Heat-developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-03-27 EP disclosed