SCHEMBL21234556

SCHEMBL21234556

CCCCCCCCCC(=O)Nc1cccc(O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.65
LMNA P02545 2/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
POLB P06746 2/20 0.61
SOAT2 O75908 1/20 0.59
SOAT1 P35610 1/20 0.59
KDM4E B2RXH2 1/20 0.58
NLRP3 Q96P20 1/20 0.58
PSMB11 A5LHX3 1/20 0.58
PSMA7 O14818 1/20 0.58
PSMB1 P20618 1/20 0.58
PSMA1 P25786 1/20 0.58
PSMA2 P25787 1/20 0.58
PSMA3 P25788 1/20 0.58
PSMA4 P25789 1/20 0.58
PSMB8 P28062 1/20 0.58
PSMB9 P28065 1/20 0.58
PSMA5 P28066 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388528 1.00 HDAC4 (0.65) HDAC4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL8741843 1.00 HDAC4 (0.65) HDAC4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL28732582 1.00 HDAC4 (0.65) HDAC4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL11132798 0.98 HDAC4 (0.63) HDAC4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL13263766 0.94 KDM4E (0.65) HDAC4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL439465 0.91 HDAC4 (0.71) HDAC4POLBNLRP3HDAC3HDAC1
SCHEMBL11901010 0.89 LMNA (0.69) HDAC4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL2885788 0.87 NLRP3 (0.64) HDAC4NLRP3ALDH1A1CYP1A2
SCHEMBL441932 0.87 HDAC4 (0.67) HDAC4POLBNLRP3HDAC3HDAC1
SCHEMBL10894945 0.87 FNTA (0.62) HDAC4LMNANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11199776-B2 Resin composition TORAY INDUSTRIES, INC. (JP) 2021-12-14 US disclosed
US-20190241716-A1 RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2019-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241716-A1 RESIN COMPOSITION SLC7A1, F12, SLCO2A1 HDAC4 2694/4885LMNA 2296/4885NPC1 2265/4885
US-11199776-B2 Resin composition SLC7A1, F12, SLCO2A1 HDAC4 2694/4885LMNA 2296/4885NPC1 2265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.