Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.58 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.58 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.58 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.58 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.58 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.58 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.58 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.58 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.58 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388528 | 1.00 | HDAC4 (0.65) | HDAC4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8741843 | 1.00 | HDAC4 (0.65) | HDAC4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21234556 | 1.00 | HDAC4 (0.65) | HDAC4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11132798 | 0.98 | HDAC4 (0.63) | HDAC4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13263766 | 0.94 | KDM4E (0.65) | HDAC4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL439465 | 0.91 | HDAC4 (0.71) | HDAC4POLBNLRP3HDAC3HDAC1 | |
| SCHEMBL11901010 | 0.89 | LMNA (0.69) | HDAC4LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2885788 | 0.87 | NLRP3 (0.64) | HDAC4NLRP3ALDH1A1CYP1A2 | |
| SCHEMBL441932 | 0.87 | HDAC4 (0.67) | HDAC4POLBNLRP3HDAC3HDAC1 | |
| SCHEMBL10894945 | 0.87 | FNTA (0.62) | HDAC4LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109896918-B | Unsaturated carbonyl compound and preparation method and application thereof | 北京大学深圳研究生院 | 2022-05-06 | — | — | CN | disclosed |