Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850223 | 0.94 | HIF1A (0.42) | HIF1AALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL9850114 | 0.92 | HIF1A (0.44) | HIF1AALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL9850095 | 0.90 | RARA (0.47) | ALDH1A1TDP1TSHRL3MBTL1RXRA | |
| SCHEMBL9850290 | 0.89 | MAPT (0.41) | ALDH1A1TDP1CYP3A4TSHRMAPK1 | |
| SCHEMBL9850227 | 0.88 | RXRA (0.48) | TSHRRXRARARARARB | |
| SCHEMBL9850140 | 0.87 | MAPT (0.41) | ALDH1A1CYP3A4TSHRL3MBTL1RXRA | |
| SCHEMBL9850220 | 0.86 | RARA (0.46) | HIF1AALDH1A1TDP1TSHRL3MBTL1 | |
| SCHEMBL9850216 | 0.83 | RARA (0.49) | ALDH1A1TDP1TSHRL3MBTL1RXRA | |
| SCHEMBL9850094 | 0.83 | MAPT (0.43) | HIF1AALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL9850206 | 0.81 | HIF1A (0.49) | HIF1AALDH1A1TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |