Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850095 | 0.94 | RARA (0.47) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850094 | 0.94 | MAPT (0.43) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850263 | 0.92 | MAPT (0.45) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850140 | 0.91 | MAPT (0.41) | MAPTKMT2ARARARARBALDH1A1 | |
| SCHEMBL9850227 | 0.90 | RXRA (0.48) | RARARARBRXRATSHR | |
| SCHEMBL9850306 | 0.89 | HIF1A (0.41) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850216 | 0.87 | RARA (0.49) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850132 | 0.87 | RARA (0.51) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850172 | 0.86 | RXRA (0.46) | MAPTKMT2ARARARARBMEN1 | |
| SCHEMBL9850280 | 0.84 | RXRA (0.41) | MAPTKMT2ARARARARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |