Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9850559 | 0.84 | MEN1 (0.46) | MEN1KMT2AGLO1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9850493 | 0.83 | MEN1 (0.52) | MEN1KMT2AGLO1TDP1MAPT | |
| SCHEMBL9850444 | 0.82 | INSR (0.41) | MEN1KMT2AMAPTALDH1A1BLM | |
| SCHEMBL522650 | 0.81 | MEN1 (0.59) | MEN1KMT2AGLO1TDP1MAPT | |
| SCHEMBL9850257 | 0.81 | MEN1 (0.51) | MEN1KMT2AGLO1TDP1MAPT | |
| SCHEMBL9850623 | 0.80 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL9850488 | 0.80 | MAPT (0.54) | MEN1KMT2AGLO1TDP1MAPT | |
| SCHEMBL9850386 | 0.80 | MEN1 (0.64) | MEN1KMT2AGLO1TDP1MAPT | |
| SCHEMBL9850544 | 0.79 | CA12 (0.53) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1008539 | 0.79 | MEN1 (0.59) | MEN1KMT2AGLO1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |