Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850466 | 0.84 | HTR1A (0.89) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850428 | 0.80 | ALDH1A1 (0.60) | MAPTKAT2BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9850407 | 0.79 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL9850591 | 0.78 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL9850606 | 0.78 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6198859 | 0.78 | KAT2B (0.80) | MAPTKAT2BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23202935 | 0.75 | CCNC (0.74) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL9850357 | 0.75 | PDE10A (0.57) | MAPTKAT2BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30827842 | 0.75 | CCNC (0.74) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL9850697 | 0.74 | HTR1A (0.66) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |