Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850498 | 0.83 | BCHE (0.49) | JAK2JAK1KDM4EALDH1A1MAPT | |
| SCHEMBL9850444 | 0.81 | INSR (0.41) | JAK2KDM4EMEN1NSD2ALDH1A1 | |
| SCHEMBL9850510 | 0.80 | MEN1 (0.43) | KDM4EMEN1NSD2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9850493 | 0.80 | MEN1 (0.52) | KDM4EMEN1NSD2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9850592 | 0.78 | BCHE (0.52) | KDM4EMEN1NSD2ALDH1A1MAPT | |
| SCHEMBL522650 | 0.78 | MEN1 (0.59) | KDM4EMEN1NSD2ALDH1A1MAPT | |
| SCHEMBL9850437 | 0.78 | HTR1A (0.61) | JAK2JAK1TDO2BRAFRAF1 | |
| SCHEMBL9850549 | 0.77 | NOS1 (0.54) | JAK2JAK1MEN1ALDH1A1MAPT | |
| SCHEMBL9850499 | 0.75 | HTR1A (0.64) | KDM4EMEN1NSD2ALDH1A1MAPT | |
| SCHEMBL9850257 | 0.75 | MEN1 (0.51) | KDM4EMEN1NSD2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |