Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649628 | 0.87 | CA9 (0.48) | MAPTLMNACYP3A4SLC6A9ALDH1A1 | |
| SCHEMBL9850686 | 0.87 | ALDH1A1 (0.49) | KMT2ASLC6A9ALDH1A1HPGDPTGDR2 | |
| SCHEMBL8656394 | 0.87 | PTGDR2 (0.47) | MAPTMEN1KMT2ANR1I2LMNA | |
| SCHEMBL9850680 | 0.86 | SLC6A9 (0.41) | MAPTMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL16950716 | 0.84 | SLC6A9 (0.43) | MAPTMEN1KMT2AHSD17B10SLC6A9 | |
| SCHEMBL13959852 | 0.80 | MAPT (0.42) | MAPTMEN1KMT2ANR1I2LMNA | |
| SCHEMBL12180298 | 0.79 | MAPT (0.51) | MAPTMEN1KMT2ANR1I2LMNA | |
| SCHEMBL16430427 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2ANR1I2LMNA | |
| SCHEMBL7647898 | 0.78 | MAPT (0.50) | MAPTLMNACYP3A4SLC6A9ALDH1A1 | |
| SCHEMBL13961577 | 0.78 | MEN1 (0.43) | MAPTMEN1KMT2ANR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442204-A2 | Pyrimidopyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-08-21 | — | — | EP | disclosed |