Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16155909 | 0.84 | GAA (0.42) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL2150032 | 0.69 | IDO1 (0.36) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL9197031 | 0.67 | GAA (0.33) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL2001603 | 0.63 | — | — | |
| SCHEMBL9197036 | 0.61 | GAA (0.32) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL3948699 | 0.60 | ALDH1A1 (0.34) | — | |
| SCHEMBL14363747 | 0.60 | CHRNB2 (0.38) | — | |
| SCHEMBL9850831 | 0.60 | — | — | |
| SCHEMBL5758572 | 0.60 | GAA (0.55) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL2113156 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416740-A2 | Novel compounds with renin-inhibiting activity | Beecham Group p.l.c. (GB) | 1991-03-13 | — | — | EP | disclosed |
| US-4451650-A | ANTITUMOR AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1984-05-29 | — | — | US | disclosed |
| US-4451650-A | ANTITUMOR AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0107130-A1 | Pyrido(4,3-b)(1,4) oxazines and pyrido(4,3-b) (1,4)thiazines | Southern Research Institute (US) | 1984-05-02 | — | — | EP | disclosed |
| EP-0107130-A1 | Pyrido(4,3-b)(1,4) oxazines and pyrido(4,3-b) (1,4)thiazines | Southern Research Institute (US) | 1984-05-02 | — | — | EP | disclosed |