Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501055 | 0.82 | OPRM1 (0.47) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL10859209 | 0.78 | OPRM1 (0.39) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL17284444 | 0.75 | TRPM8 (0.54) | TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL11215068 | 0.74 | TRPM8 (0.42) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL27797531 | 0.74 | TRPM8 (0.42) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| Menthol SCHEMBL27673361 | 0.71 | TRPM8 (0.78) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL21380098 | 0.70 | TRPM8 (0.48) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL28083608 | 0.70 | OPRM1 (0.45) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL1862576 | 0.70 | TRPM8 (0.48) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 | |
| SCHEMBL7606663 | 0.70 | TRPM8 (0.44) | OPRM1TRPM8TRPA1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |