Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203206 | 0.75 | ADORA3 (0.52) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7430342 | 0.71 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9197994 | 0.68 | PGR (0.58) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL16099173 | 0.67 | PARP1 (0.45) | ADORA3NPC1POLB | |
| SCHEMBL515771 | 0.66 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Hydrochloric Acid SCHEMBL9207762 | 0.66 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Ammonia Solution, Strong SCHEMBL10420651 | 0.65 | PDE4A (0.97) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7460178 | 0.64 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4623455 | 0.64 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL4423680 | 0.64 | ADORA2B (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411394-A1 | Imidazoquinolone derivates | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-06 | — | — | EP | claimed |