Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 9/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197994 | 0.92 | PGR (0.58) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9204684 | 0.89 | ALDH1A1 (0.49) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6472578 | 0.83 | ADORA2A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9851040 | 0.75 | PDE4A (0.49) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16099173 | 0.74 | PARP1 (0.45) | ADORA3KDM4EGAAPGRLMNA | |
| SCHEMBL9208527 | 0.74 | ADORA3 (0.53) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9851037 | 0.72 | LMNA (0.50) | ADORA3ADORA2AADORA2BKDM4EGAA | |
| SCHEMBL9198164 | 0.71 | PDE4A (0.58) | ADORA3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9218908 | 0.69 | PLK1 (0.46) | ADORA3KDM4EGAAPGRRORA | |
| SCHEMBL13386557 | 0.69 | ALDH1A1 (0.71) | ADORA3KDM4EGAAPGRRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411394-B1 | Imidazoquinolone derivates | KYOWA HAKKO KOGYO KK (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5010084-A | Antihistamines; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0411394-A1 | Imidazoquinolone derivates | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |