Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674976 | 0.76 | PPOX (0.40) | PPOXKDM4ENPC1MITFTHRB | |
| SCHEMBL9837229 | 0.73 | KDM4E (0.48) | PPOXKDM4ENPC1MITFTHRB | |
| SCHEMBL8849136 | 0.73 | PPOX (0.41) | PPOXKDM4ERORCLMNACYP1A2 | |
| SCHEMBL19088271 | 0.72 | PPOX (0.46) | PPOXKDM4ERAB9ARORCLMNA | |
| SCHEMBL19088273 | 0.70 | PPOX (0.45) | PPOXKDM4ERAB9ARORCLMNA | |
| SCHEMBL30902485 | 0.69 | LMNA (0.47) | PPOXKDM4ERORCLMNACYP1A2 | |
| SCHEMBL16200095 | 0.68 | KDM4E (0.46) | PPOXKDM4ERAB9ARORCLMNA | |
| SCHEMBL19088275 | 0.67 | PPOX (0.42) | PPOXKDM4ERAB9ARORCLMNA | |
| SCHEMBL8599602 | 0.66 | PPOX (0.45) | PPOXKDM4ENPC1MAPK1RAB9A | |
| SCHEMBL8157623 | 0.66 | KDM4E (0.49) | KDM4EMAPK1RAB9ARORCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416361-A1 | N-(5-alkyl thiophenyl)-nitrogenheterocycles | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |