Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L11 | O43521 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694976 | 0.76 | ALDH1A1 (0.39) | TSHRMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL14346586 | 0.73 | MAPT (0.56) | TSHRMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL28468678 | 0.72 | KDM4E (0.49) | TSHRLMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL14721112 | 0.72 | LMNA (0.54) | TSHRMAPTLMNAALDH1A1HSD17B10 | |
| SCHEMBL1223851 | 0.72 | MAPT (0.61) | TSHRMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL3173137 | 0.70 | MAPT (0.49) | TSHRMAPTLMNACYP1A2CYP2C9 | |
| SCHEMBL1093254 | 0.70 | MAPT (0.43) | TSHRMAPTLMNACYP1A2ALDH1A1 | |
| SCHEMBL3162185 | 0.70 | L3MBTL1 (0.60) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12058772 | 0.70 | ESR1 (0.47) | BCL2L11BCL2L1MCL1TSHRLMNA | |
| SCHEMBL28754525 | 0.70 | GAA (0.54) | MAPTLMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416361-A1 | N-(5-alkyl thiophenyl)-nitrogenheterocycles | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |