Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 17/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 12/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851343 | 0.73 | ACHE (0.51) | ACHEKDM4EMITFALDH1A1LMNA | |
| SCHEMBL12043410 | 0.72 | ACHE (1.00) | ACHEBCHECHRM1GRIN1GRIN2A | |
| SCHEMBL30410668 | 0.72 | ACHE (1.00) | ACHEBCHECHRM1GRIN1GRIN2A | |
| SCHEMBL9851360 | 0.71 | ACHE (0.51) | ACHEKDM4EALDH1A1LMNABCHE | |
| Hydrochloric Acid SCHEMBL9851361 | 0.68 | ALDH1A1 (0.49) | ACHEKDM4EMITFALDH1A1LMNA | |
| SCHEMBL10490519 | 0.67 | HRH3 (0.52) | ALDH1A1 | |
| SCHEMBL29679617 | 0.65 | ACHE (0.51) | ACHEBCHECHRM1GRIN1GRIN2A | |
| SCHEMBL9255540 | 0.65 | ACHE (0.60) | ACHEKDM4EALDH1A1BCHECHRM1 | |
| SCHEMBL4491778 | 0.64 | ALDH1A1 (0.61) | ACHEKDM4EALDH1A1LMNABCHE | |
| SCHEMBL28500602 | 0.64 | ALDH1A1 (0.50) | ACHEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0430485-A2 | Quinoline compound | UBE INDUSTRIES, LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |