Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13155057 | 0.83 | AURKA (0.47) | NOS3NOS1NOS2KMT2AAURKA | |
| SCHEMBL9705274 | 0.83 | NOS3 (0.48) | NOS3NOS1NOS2KMT2API4KA | |
| SCHEMBL9570281 | 0.83 | AURKA (0.43) | NOS3NOS1NOS2KMT2AAURKA | |
| SCHEMBL9598614 | 0.83 | AURKA (0.43) | NOS3NOS1NOS2KMT2AAURKA | |
| SCHEMBL7388204 | 0.76 | NOS3 (0.43) | NOS3NOS1NOS2PI4KAPI4K2B | |
| SCHEMBL7851163 | 0.76 | PI4KA (0.49) | NOS3NOS1NOS2PI4KAPI4K2B | |
| SCHEMBL9203040 | 0.74 | SMN1; SMN2 (0.49) | NOS3NOS1NOS2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9704690 | 0.74 | PI4KA (0.43) | NOS3NOS1NOS2KMT2API4KA | |
| SCHEMBL7853172 | 0.74 | HPGD (0.46) | NOS3NOS1NOS2KMT2API4KA | |
| SCHEMBL9720980 | 0.73 | KMT2A (0.84) | KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434038-A1 | Fused imidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-06-26 | — | — | EP | disclosed |