Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.35 |
| ▸ | ATG7 | O95352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851714 | 0.88 | ALDH1A1 (0.43) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9851704 | 0.88 | ALDH1A1 (0.39) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9851804 | 0.85 | NT5E (0.41) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9851855 | 0.84 | NT5E (0.37) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9851711 | 0.84 | MAPT (0.45) | STING1LMNANT5EMAPTTYMP | |
| SCHEMBL9851876 | 0.81 | NT5E (0.40) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL9851743 | 0.81 | ATG7 (0.52) | STING1ALDH1A1LMNANT5ETYMP | |
| SCHEMBL9851916 | 0.81 | LPAR1 (0.36) | STING1ALDH1A1NT5E | |
| SCHEMBL9851779 | 0.81 | LPAR1 (0.36) | STING1ALDH1A1NT5E | |
| SCHEMBL9851863 | 0.81 | LPAR1 (0.36) | STING1ALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | claimed |
| EP-0450102-A1 | NUCLEOSIDE DERIVATIVE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-10-09 | — | — | EP | disclosed |