Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.62 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872559 | 0.84 | DRD4 (0.78) | DRD4SIGMAR1MCHR1CCR3MEN1 | |
| SCHEMBL9727182 | 0.83 | DRD4 (0.64) | DRD4SIGMAR1MCHR1CCR3ALDH1A1 | |
| SCHEMBL9727092 | 0.82 | DRD4 (0.63) | DRD4SIGMAR1MCHR1CCR3ALDH1A1 | |
| SCHEMBL9727190 | 0.82 | DRD4 (0.62) | DRD4SIGMAR1MCHR1CCR3 | |
| SCHEMBL9727147 | 0.82 | SIGMAR1 (0.60) | DRD4SIGMAR1MCHR1MEN1KMT2A | |
| SCHEMBL9727145 | 0.82 | SIGMAR1 (0.60) | DRD4SIGMAR1MCHR1MEN1KMT2A | |
| SCHEMBL9727102 | 0.82 | SIGMAR1 (0.72) | DRD4SIGMAR1MCHR1CCR3MEN1 | |
| SCHEMBL5862230 | 0.79 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL15171718 | 0.79 | MCHR1 (0.71) | DRD4SIGMAR1MCHR1CCR3KMT2A | |
| SCHEMBL14492763 | 0.78 | L3MBTL1 (0.67) | DRD4SIGMAR1MCHR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |
| US-5028616-A | Antiarrhythmia Agents | G. D. SEARLE & CO. (US) | 1991-07-02 | — | — | US | disclosed |