Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.75 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16233177 | 0.91 | SLC6A5 (0.84) | SLC6A5MCHR1DRD4MEN1KMT2A | |
| SCHEMBL9870172 | 0.90 | MEN1 (0.78) | MCHR1DRD4MEN1KMT2ATMEM97 | |
| SCHEMBL9870566 | 0.87 | MEN1 (0.73) | MCHR1DRD4MEN1KMT2ATMEM97 | |
| SCHEMBL9871439 | 0.84 | UTS2R (0.69) | SLC6A5MCHR1DRD4MEN1KMT2A | |
| SCHEMBL9872559 | 0.83 | DRD4 (0.78) | MCHR1DRD4MEN1KMT2ASIGMAR1 | |
| SCHEMBL694949 | 0.83 | SIGMAR1 (0.82) | MCHR1DRD4MEN1KMT2ATMEM97 | |
| SCHEMBL17946118 | 0.81 | ADIPOR2 (0.88) | MCHR1DRD4MEN1KMT2ASIGMAR1 | |
| SCHEMBL61848 | 0.80 | TMEM97 (0.83) | MCHR1DRD4MEN1KMT2ATMEM97 | |
| SCHEMBL7218171 | 0.80 | TMEM97 (0.74) | SLC6A5MCHR1DRD4MEN1KMT2A | |
| SCHEMBL1477287 | 0.79 | SLC6A5 (0.65) | SLC6A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |
| US-5028616-A | Antiarrhythmia Agents | G. D. SEARLE & CO. (US) | 1991-07-02 | — | — | US | disclosed |