SCHEMBL9852316

SCHEMBL9852316

CC(=O)Nc1cc(OCCO)cc(NC(C)=O)n1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 13/20 0.48
ADORA2A P29274 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 1/20 0.44
ADORA1 P30542 5/20 0.44
ABL1 P00519 1/20 0.43
MAPK8 P45983 3/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
MAP4K2 Q12851 1/20 0.42
PKN2 Q16513 1/20 0.42
MAP4K5 Q9Y4K4 1/20 0.42
ADORA2B P29275 3/20 0.42
MAPK9 P45984 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19736187 0.83 PIK3C3 (0.50) L3MBTL1ABL1
SCHEMBL9813293 0.78 TSHR (0.43) ADORA3ADORA2AL3MBTL1MAPK8PRKD3
SCHEMBL9813328 0.78 CHRNB2 (0.46) ADORA3ADORA2AL3MBTL1MAPK8PRKD3
SCHEMBL3915926 0.77 ALDH1A1 (0.44) L3MBTL1ALDH1A1
SCHEMBL19736190 0.75 ALDH1A1 (0.46) L3MBTL1ALDH1A1
SCHEMBL19706717 0.73 MAPK8 (0.73) ADORA3ADORA2AL3MBTL1ADORA1MAPK8
SCHEMBL19706526 0.73 MAPK8 (0.46) ADORA3ADORA2AL3MBTL1ADORA1MAPK8
SCHEMBL19706493 0.73 CYP1A2 (0.48) ADORA3ADORA2AL3MBTL1ADORA1MAPK8
SCHEMBL28907999 0.73 L3MBTL1 (0.48) ADORA3ADORA2AL3MBTL1ADORA1MAPK8
SCHEMBL92223 0.72 ALDH1A1 (0.78) L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433188-A1 Possibly thermotropic polymolecular associations based on hydrogen bonded monomers, process for their preparation and monomers for carrying out this process RHONE-POULENC CHIMIE (FR) 1991-06-19 EP disclosed