Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783882 | 0.85 | MMP2 (0.36) | MAPT | |
| SCHEMBL27373480 | 0.83 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9852510 | 0.77 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9504024 | 0.77 | CHRNB2 (0.42) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6421932 | 0.75 | RECQL (0.44) | ALDH1A1MAPT | |
| SCHEMBL2973540 | 0.74 | FAAH (0.42) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9777085 | 0.73 | CHRNB2 (0.41) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5001742 | 0.72 | CHRNB2 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7106155 | 0.72 | CHRNB2 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8466699 | 0.72 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425978-A2 | Nitroguanidine compounds and insecticides | AGRO-KANESHO CO., LTD. (JP) | 1991-05-08 | — | — | EP | claimed |