Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.32 |
| ▸ | PPOX | P50336 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445807 | 0.81 | RIPK1 (0.40) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9852614 | 0.72 | GFER (0.47) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9852609 | 0.72 | PPOX (0.39) | PPOX | |
| SCHEMBL8553521 | 0.69 | PGK1 (0.39) | MAPTALDH1A1MAPK1SNCAATM | |
| SCHEMBL21177279 | 0.68 | SNCA (0.48) | GAAMAPTALDH1A1SNCAATM | |
| SCHEMBL25532029 | 0.68 | ATM (0.49) | GAAMAPTALDH1A1SNCAATM | |
| SCHEMBL11117152 | 0.67 | MAOB (0.41) | MAPTMAPK1SMN1; SMN2RAB9APTGS1 | |
| SCHEMBL6968277 | 0.66 | SMN1; SMN2 (0.55) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31388416 | 0.66 | GAA (0.68) | GAAMAPTALDH1A1KMT2AATM | |
| SCHEMBL31717819 | 0.66 | GAA (0.68) | GAAMAPTALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444764-A1 | Process and intermediates for the preparation of substituted 1-benzothiazolyl-3,4-dimethyl-3-pyrrolin-2,5(1H)-diones | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-04 | — | — | EP | disclosed |