Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587734 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL10588292 | 0.90 | FAAH (0.46) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL10588293 | 0.90 | FAAH (0.46) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL756847 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL2780950 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL9631551 | 0.81 | CTSS (0.60) | CTSSCTSLMMP8 | |
| SCHEMBL9631546 | 0.81 | CTSS (0.60) | CTSSCTSLMMP8 | |
| SCHEMBL9631257 | 0.80 | POLB (0.53) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL10586443 | 0.80 | CTSS (0.51) | KDM4EALDH1A1TSHRHSD17B10CTSS | |
| SCHEMBL10587171 | 0.80 | CTSS (0.47) | KDM4EALDH1A1TSHRHSD17B10CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |