Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588292 | 1.00 | FAAH (0.46) | FAAHCYP3A4CALCRLKMT2AMEN1 | |
| SCHEMBL9852728 | 0.90 | KDM4E (0.53) | FAAHKMT2AMEN1MMP9CTSS | |
| SCHEMBL10587734 | 0.90 | KDM4E (0.53) | FAAHKMT2AMEN1MMP9CTSS | |
| SCHEMBL8944896 | 0.79 | TACR1 (0.51) | KMT2AMEN1CTNNB1HRH4MME | |
| SCHEMBL2269285 | 0.79 | TACR1 (0.51) | KMT2AMEN1CTNNB1HRH4MME | |
| SCHEMBL9852735 | 0.76 | ANPEP (0.49) | KMT2AMEN1CTNNB1HRH4MME | |
| SCHEMBL9631571 | 0.73 | CTNNB1 (0.45) | CTNNB1HRH4MMEACECPA1 | |
| SCHEMBL9727658 | 0.73 | CTNNB1 (0.45) | CTNNB1HRH4MMEACECPA1 | |
| SCHEMBL10305134 | 0.73 | HRH2 (0.54) | KMT2AMEN1CTNNB1LMNA | |
| SCHEMBL10477667 | 0.72 | CASP1 (0.54) | CYP3A4HRH4CTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |