Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544632 | 0.86 | CTNNB1 (0.52) | CASP1MMEACECPA1ACE2 | |
| SCHEMBL2269291 | 0.85 | TACR1 (0.51) | CASP1MMEACECPA1ACE2 | |
| SCHEMBL2270111 | 0.85 | TACR1 (0.51) | CASP1MMEACECPA1ACE2 | |
| SCHEMBL7445998 | 0.80 | CAPN1 (0.55) | ACECAPN1CTSKCTSL | |
| SCHEMBL9852735 | 0.79 | ANPEP (0.49) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL25660784 | 0.79 | CTNNB1 (0.45) | CASP1CTNNB1KMT2AMTNR1AMMP9 | |
| SCHEMBL9631575 | 0.79 | CTNNB1 (0.45) | CASP1CTNNB1KMT2AMTNR1AMMP9 | |
| SCHEMBL9727662 | 0.79 | CTNNB1 (0.45) | CASP1CTNNB1KMT2AMTNR1AMMP9 | |
| SCHEMBL10477668 | 0.78 | CASP1 (0.54) | CASP1CAPN1HRH4 | |
| SCHEMBL6443453 | 0.75 | ATM (0.44) | MMEACECPA1ACE2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |