SCHEMBL9852781

SCHEMBL9852781

Cc1nc(OC(N)=O)nc(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
NNMT P40261 1/20 0.32
ALOX15 P16050 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9852833 0.79 PDE10A (0.33) KMT2A
SCHEMBL6628690 0.76 KMT2A (0.51) KMT2AALDH1A1MEN1
SCHEMBL9852813 0.76 NPSR1 (0.34) KMT2AALDH1A1GAAHPGD
SCHEMBL9256983 0.72 GAA (0.35) NNMTALDH1A1GAA
SCHEMBL28456316 0.69 MAPK1 (0.43) KMT2ANNMTALDH1A1GAAHPGD
SCHEMBL8109431 0.68 LMNA (0.50) NNMTALDH1A1
SCHEMBL28643764 0.67 HSD17B10 (0.42) KMT2AMEN1
SCHEMBL29079918 0.67 POLB (0.34)
SCHEMBL29048006 0.67 KMT2A (0.39) KMT2AALDH1A1MEN1
SCHEMBL10363495 0.66 KMT2A (0.46) KMT2AALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0444286-A1 Sulphonylated pyrimidine carboxylic acid amides BAYER AG (DE) 1991-09-04 EP disclosed