Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445995 | 0.84 | NPC1 (0.49) | ANPEPNPC1RAB9AEPHX2 | |
| SCHEMBL8357480 | 0.79 | HDAC2 (0.53) | MAPT | |
| SCHEMBL8357478 | 0.79 | HDAC2 (0.53) | MAPT | |
| SCHEMBL9852784 | 0.78 | KMT2A (0.60) | KMT2AMEN1TSHREPHX1ANPEP | |
| SCHEMBL9871281 | 0.77 | ALDH1A1 (0.60) | NPC1RAB9APSMB5 | |
| SCHEMBL6032606 | 0.77 | EPHX1 (0.85) | KMT2AMEN1TSHREPHX1NPC1 | |
| SCHEMBL10725488 | 0.77 | SMN1; SMN2 (0.57) | — | |
| SCHEMBL10725478 | 0.77 | SMN1; SMN2 (0.57) | — | |
| SCHEMBL8837504 | 0.77 | CTRB1 (0.60) | KMT2AMEN1TSHREPHX1ANPEP | |
| SCHEMBL29687117 | 0.77 | KMT2A (0.75) | KMT2AMEN1TSHREPHX1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |