Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852783 | 0.84 | KMT2A (0.59) | NPC1RAB9AANPEPEPHX2 | |
| SCHEMBL27698308 | 0.81 | CTSC (0.54) | NPC1RAB9ACTSCLMNAALDH1A1 | |
| SCHEMBL334301 | 0.81 | CTRB1 (0.57) | NPC1RAB9ACTSCLMNAACACB | |
| SCHEMBL2843211 | 0.81 | CTRB1 (0.57) | NPC1RAB9ACTSCLMNAACACB | |
| SCHEMBL334424 | 0.81 | CTRB1 (0.57) | NPC1RAB9ACTSCLMNAACACB | |
| SCHEMBL12204095 | 0.80 | NPC1 (0.77) | NPC1RAB9ALMNAGAAACACB | |
| SCHEMBL10429991 | 0.80 | LMNA (0.67) | POLBLMNAATMALDH1A1ANPEP | |
| SCHEMBL26258443 | 0.80 | NPC1 (0.77) | NPC1RAB9ALMNAGAAACACB | |
| SCHEMBL9852735 | 0.79 | ANPEP (0.49) | ANPEPCTSSCTSK | |
| SCHEMBL6292023 | 0.78 | NPC1 (0.47) | NPC1RAB9ACTSCPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748333-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0748333-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023809-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |