SCHEMBL9853399

SCHEMBL9853399

O=CNCc1ccccc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH7 P40394 1/20 0.46
MYC P01106 1/20 0.39
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 1/20 0.36
EGFR P00533 1/20 0.35
TSHR P16473 3/20 0.34
CYP2D6 P10635 2/20 0.34
CA12 O43570 5/20 0.34
CA2 P00918 5/20 0.34
CA9 Q16790 4/20 0.34
KDM4E B2RXH2 1/20 0.34
TTR P02766 2/20 0.34
FABP4 P15090 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11807158 0.79 CA12 (0.58) HSD17B10TSHRCYP2D6CA12CA2
SCHEMBL8719378 0.79 HIF1A (0.46) MYCHIF1AHSD17B10LMNAHPGD
SCHEMBL8763191 0.78 ADH1B (0.62) ADH1BADH1CADH1AADH7HIF1A
SCHEMBL30595834 0.78 ADH1B (0.62) ADH1BADH1CADH1AADH7HIF1A
SCHEMBL9769575 0.78 MAPT (0.42) MYCLMNATSHRCA12CA2
SCHEMBL9768531 0.78 MYC (0.44) MYCLMNACA2KDM4ETTR
SCHEMBL9516851 0.76 MAPT (0.41) MYCLMNATSHRCA12CA2
SCHEMBL9853396 0.75 MYC (0.39) MYCLMNAEGFRTSHRCYP2D6
SCHEMBL10350291 0.75 HIF1A (0.47) HIF1AEGFRCA12CA2CA9
SCHEMBL19932515 0.74 EGFR (0.36) ADH1BADH1CADH1AADH7HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409117-A1 Silver halide photographic material KONICA CORPORATION (JP) 1991-01-23 EP disclosed