SCHEMBL9853396

SCHEMBL9853396

O=[C]NCc1ccccc1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.39
ADRA1D P25100 2/20 0.35
TTR P02766 2/20 0.34
FABP4 P15090 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
MAPK14 Q16539 1/20 0.34
MMP1 P03956 3/20 0.34
MMP2 P08253 3/20 0.34
MMP3 P08254 3/20 0.34
MMP9 P14780 3/20 0.34
MMP12 P39900 3/20 0.34
MMP13 P45452 3/20 0.34
MMP14 P50281 3/20 0.34
MMP8 P22894 2/20 0.34
MMP16 P51512 2/20 0.34
CA12 O43570 3/20 0.33
NR4A1 P22736 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853405 0.78 TIMP3 (0.37) CA12LMNATSHRSMN1; SMN2ALDH1A1
SCHEMBL9769575 0.78 MAPT (0.42) MYCTTRFABP4CCNA2CDK2
SCHEMBL9768531 0.78 MYC (0.44) MYCTTRFABP4CCNA2CDK2
SCHEMBL9516851 0.76 MAPT (0.41) MYCTTRFABP4CCNA2CDK2
SCHEMBL10414833 0.76 MYC (0.42) MYCTTRFABP4CCNA2CDK2
SCHEMBL8719378 0.75 HIF1A (0.46) MYCADRA1DCA12LMNATSHR
SCHEMBL9853399 0.75 ADH1B (0.46) MYCTTRFABP4CCNA2CDK2
SCHEMBL11807158 0.75 CA12 (0.58) CA12TSHRCA9CA2CYP2D6
SCHEMBL10350291 0.75 HIF1A (0.47) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL14991455 0.74 MYC (0.47) MYCTTRFABP4CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409117-A1 Silver halide photographic material KONICA CORPORATION (JP) 1991-01-23 EP disclosed