Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853554 | 1.00 | LMNA (0.42) | LMNAMAPTKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL9853478 | 0.81 | TERT (0.46) | MAPTKDM4ECYP1A2HTTKMT2A | |
| SCHEMBL4584462 | 0.76 | KDM4E (0.51) | LMNAMAPTKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL4584461 | 0.76 | KDM4E (0.51) | LMNAMAPTKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL29002664 | 0.75 | GLA (0.46) | LMNAMAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9868747 | 0.74 | KDM4E (0.46) | MAPTKDM4EF2F10PRSS1 | |
| SCHEMBL9853516 | 0.72 | MAPT (0.56) | LMNAMAPTCYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL10648968 | 0.72 | KDM4E (0.42) | LMNAMAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9986917 | 0.70 | F2 (0.39) | HTTKMT2AMEN1F2F10 | |
| SCHEMBL12070369 | 0.70 | F2 (0.39) | MAPTCYP1A2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015476-A1 | SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES | DOWELANCO (US) | 1991-10-17 | — | — | WO | disclosed |
| EP-0450712-A2 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1991-10-09 | — | — | EP | disclosed |
| US-5013352-A | Grassy weeds in presence of crops | DOWELANCO (US) | 1991-05-07 | — | — | US | disclosed |