SCHEMBL9853478

SCHEMBL9853478

CSc1ccc(Oc2cccc(C=O)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 9/20 0.46
ALDH1A1 P00352 2/20 0.41
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
ST14 Q9Y5Y6 1/20 0.36
CYP1A1 P04798 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP1B1 Q16678 2/20 0.36
SLC6A4 P31645 2/20 0.35
HTR2A P28223 1/20 0.35
KCNH2 Q12809 1/20 0.35
NPBWR1 P48145 1/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11149465 0.83 KDM4E (0.50) TERTALDH1A1F2F10PRSS1
SCHEMBL10988595 0.83 TERT (0.52) TERTALDH1A1F2F10PRSS1
SCHEMBL9853557 0.81 LMNA (0.42) TERTALDH1A1F2F10PRSS1
SCHEMBL9853554 0.81 LMNA (0.42) TERTALDH1A1F2F10PRSS1
SCHEMBL9540409 0.80 LMNA (0.43) TERTALDH1A1F2F10PRSS1
SCHEMBL10708134 0.80 L3MBTL1 (0.50) TERTALDH1A1F2F10PRSS1
SCHEMBL9818059 0.80 TERT (0.46) TERTF2F10PRSS1PRSS2
SCHEMBL9986917 0.76 F2 (0.39) F2F10PRSS1PRSS2PRSS3
SCHEMBL12070369 0.76 F2 (0.39) F2F10PRSS1PRSS2PRSS3
SCHEMBL10977276 0.76 DRD1 (0.45) TERTALDH1A1F2F10PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991015476-A1 SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES DOWELANCO (US) 1991-10-17 WO disclosed
EP-0450712-A2 Substituted cyclohexanediones and their herbicidal uses DOWELANCO (US) 1991-10-09 EP disclosed
US-5013352-A Grassy weeds in presence of crops DOWELANCO (US) 1991-05-07 US disclosed