SCHEMBL9853575

SCHEMBL9853575

N=C(N)/C(=C/C(=O)NN)C(=O)NN.Nc1ccc(Cl)cc1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.42
GFER P55789 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
S100B P04271 1/20 0.41
MAPT P10636 4/20 0.40
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.40
MITF O75030 1/20 0.40
HSP90AA1 P07900 1/20 0.40
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TLR9 Q9NR96 1/20 0.40
ALOX15 P16050 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
TP53 P04637 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853500 0.77 RECQL (0.48) RECQLGFERKMT2ASMN1; SMN2S100B
SCHEMBL31000389 0.77 RECQL (0.67) RECQLGFERKMT2ASMN1; SMN2S100B
SCHEMBL30484136 0.77 RECQL (0.67) RECQLGFERKMT2ASMN1; SMN2S100B
SCHEMBL145366 0.77 RECQL (0.67) RECQLGFERKMT2ASMN1; SMN2S100B
Hydrochloric Acid SCHEMBL27581315 0.75 RECQL (0.65) RECQLGFERKMT2ASMN1; SMN2S100B
Hydrazine SCHEMBL11821861 0.75 RECQL (0.65) RECQLGFERKMT2ASMN1; SMN2S100B
Acetamide SCHEMBL16335345 0.74 RECQL (0.59) RECQLGFERKMT2ASMN1; SMN2S100B
SCHEMBL9853522 0.71 RECQL (0.44) RECQLGFERKMT2ASMN1; SMN2S100B
SCHEMBL6351799 0.69 RECQL (0.64) RECQLGFERKMT2ASMN1; SMN2MAPT
SCHEMBL11866382 0.69 MAPT (0.55) RECQLGFERKMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433526-A1 Medicine for the treatment of heart-circulatory illnesses, of arrhythmics in particular Richter, Peter, Prof. Dr.sc.nat. (DE) 1991-06-26 EP claimed