Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457524 | 0.93 | MAPT (0.62) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL31000389 | 0.84 | RECQL (0.67) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL145366 | 0.84 | RECQL (0.67) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL30484136 | 0.84 | RECQL (0.67) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| Hydrazine SCHEMBL11821861 | 0.83 | RECQL (0.65) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL27581315 | 0.83 | RECQL (0.65) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| Acetamide SCHEMBL16335345 | 0.79 | RECQL (0.59) | MAPTALDH1A1LMNASMN1; SMN2RECQL | |
| SCHEMBL9164786 | 0.78 | MAPT (0.58) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL11630143 | 0.78 | GABRP (0.61) | MAPTALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL27611956 | 0.77 | MAPT (0.72) | MAPTALDH1A1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947466-A | ANTIDEPRESSANTS, ANTIANXIETY | THE UPJOHN COMPANY (US) | 1976-03-30 | — | — | US | disclosed |