Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897162 | 0.89 | ALDH1A1 (0.51) | LMNAHPGDMAPK1HTTALDH1A1 | |
| SCHEMBL9297643 | 0.85 | MAPT (0.49) | LMNAHPGDMAPK1HTTALDH1A1 | |
| SCHEMBL9860244 | 0.85 | MAPT (0.51) | LMNAHPGDMAPK1HTTALDH1A1 | |
| SCHEMBL28338598 | 0.83 | MAPT (0.49) | LMNAHPGDMAPK1HTTALDH1A1 | |
| SCHEMBL30974600 | 0.83 | CTNNB1 (0.59) | LMNAHPGDHTTALDH1A1SLC6A3 | |
| SCHEMBL29250450 | 0.83 | CTNNB1 (0.59) | LMNAHPGDHTTALDH1A1SLC6A3 | |
| SCHEMBL28476280 | 0.81 | AKR1C3 (0.56) | MAPK1MAPTELANESTSSRC | |
| SCHEMBL28338529 | 0.81 | MAPK1 (0.50) | LMNAHPGDMAPK1HTTALDH1A1 | |
| SCHEMBL27511977 | 0.80 | POLB (0.55) | LMNAMAPK1HTTALDH1A1CYP1A2 | |
| SCHEMBL10697260 | 0.79 | CTNNB1 (0.53) | LMNAHPGDMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |