Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897162 | 0.87 | ALDH1A1 (0.51) | MAPTMAPK1ELANESRCTGFBR1 | |
| SCHEMBL9297643 | 0.86 | MAPT (0.49) | MAPTMAPK1ELANESRCTGFBR1 | |
| SCHEMBL9853728 | 0.85 | LMNA (0.50) | MAPTMAPK1ELANESRCTGFBR1 | |
| SCHEMBL28476280 | 0.80 | AKR1C3 (0.56) | MAPTMAPK1ELANETDP1SRC | |
| SCHEMBL7466422 | 0.79 | MAPT (0.49) | MAPTMAPK1ELANESRCTGFBR1 | |
| SCHEMBL27511977 | 0.79 | POLB (0.55) | MAPTMAPK1ELANESRCTGFBR1 | |
| SCHEMBL9853445 | 0.78 | MAPT (0.41) | MAPTMAPK1ELANESRCTGFBR1 | |
| SCHEMBL10825614 | 0.78 | HTR2A (0.51) | ELANETDP1POLBCYP1A2HPGD | |
| SCHEMBL28380211 | 0.78 | MAPT (0.65) | MAPTMAPK1ELANETDP1SRC | |
| SCHEMBL9419499 | 0.78 | SRD5A2 (0.58) | MAPTMAPK1ELANEL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446720-A2 | Novel brominated phenoxy compounds and processes for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |