Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376925 | 0.84 | KMO (0.36) | KMOALDH1A1KCNMA1PDE2APDE10A | |
| SCHEMBL5031381 | 0.81 | SMN1; SMN2 (0.41) | KMOCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL5698521 | 0.81 | KMO (0.36) | KMOCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL28355617 | 0.80 | NPC1 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL28583461 | 0.72 | NPC1 (0.44) | ALDH1A1RAB9AKDM4ENPC1MAPT | |
| SCHEMBL3857163 | 0.72 | SMN1; SMN2 (0.41) | CYP2C9CYP2C19ALDH1A1CYP2D6KCNMA1 | |
| SCHEMBL29869681 | 0.71 | NPC1 (0.43) | ALDH1A1RAB9AKDM4ENPC1MAPT | |
| SCHEMBL9798037 | 0.69 | NPC1 (0.41) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2356484 | 0.69 | KCNMA1 (0.40) | CYP1A2CYP2C9CYP2C19CYP3A4KCNMA1 | |
| SCHEMBL17767326 | 0.66 | NPC1 (0.38) | GAARAB9ANPC1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413647-A2 | Solid-form additive systems dispersible in aqueous media, methods for the preparation and application thereof to polymeric particles | EASTMAN CHEMICAL COMPANY (US) | 1991-02-20 | — | — | EP | disclosed |