Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031381 | 0.83 | SMN1; SMN2 (0.41) | KMOKCNMA1NPC1RAB9APDE2A | |
| SCHEMBL9853757 | 0.81 | KMO (0.37) | KMOKCNMA1NPC1RAB9APDE2A | |
| SCHEMBL29376925 | 0.78 | KMO (0.36) | KMOKCNMA1PDE2APDE10ACUL4A | |
| SCHEMBL3857163 | 0.73 | SMN1; SMN2 (0.41) | KCNMA1NPC1RAB9ASMN1; SMN2KDM4E | |
| Bumetrizole SCHEMBL1792777 | 0.71 | KCNMA1 (0.48) | KCNMA1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3177701 | 0.67 | KCNMA1 (0.40) | KCNMA1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL502853 | 0.65 | KCNMA1 (0.67) | KCNMA1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL6067857 | 0.65 | CHEK1 (0.39) | KCNMA1NPC1RAB9APDE2APDE10A | |
| Bumetrizole SCHEMBL8359542 | 0.65 | NPC1 (0.48) | KCNMA1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11545910 | 0.64 | NPC1 (0.53) | KMONPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599543-B1 | UV-STABILISED POLYAMIDE COMPOSITION | DSM IP ASSETS BV (NL) | 2006-08-09 | — | — | EP | disclosed |