Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9853808 | 0.99 | ALDH1A1 (0.56) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL9858685 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL9853270 | 0.84 | KDM4E (0.51) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL8075174 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAKMT2AHSD17B10 | |
| SCHEMBL9853819 | 0.82 | KDM4E (0.56) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL2441955 | 0.80 | SLC6A3 (0.65) | ALDH1A1KDM4EGAAKMT2AHSD17B10 | |
| SCHEMBL9853809 | 0.79 | KMT2A (0.50) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL31552940 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL9853794 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EGLAGAAKMT2A | |
| SCHEMBL29139940 | 0.77 | KMT2A (0.64) | ALDH1A1KDM4EGLAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |
| US-4940704-A | Pyrido[3,4-b][1,4]benzoxazepines | HOECHST-ROUSSEL PHARMACEUTICAL INC. (US) | 1990-07-10 | — | — | US | disclosed |