Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853795 | 0.82 | ALDH1A1 (0.57) | KDM4EPOLBATMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9853808 | 0.81 | ALDH1A1 (0.56) | KDM4EPOLBATMKMT2AMEN1 | |
| SCHEMBL9853809 | 0.81 | KMT2A (0.50) | KDM4EPOLBATMKMT2AMEN1 | |
| SCHEMBL9858685 | 0.80 | ALDH1A1 (0.61) | KDM4EPOLBATMKMT2AMEN1 | |
| SCHEMBL14874214 | 0.79 | KDM4E (0.59) | KDM4EPOLBATMKMT2AALDH1A1 | |
| SCHEMBL2441955 | 0.79 | SLC6A3 (0.65) | KDM4EPOLBATMKMT2AMEN1 | |
| SCHEMBL29139940 | 0.76 | KMT2A (0.64) | KDM4EKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4386585 | 0.75 | SLC6A3 (0.56) | KDM4EPOLBATMKMT2AMEN1 | |
| SCHEMBL15839759 | 0.75 | KDM4C (0.69) | KDM4EPOLBATMKMT2AALDH1A1 | |
| SCHEMBL23012320 | 0.74 | TDP1 (0.55) | KDM4EKMT2AALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |