Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853813 | 0.87 | KMT2A (0.49) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8076951 | 0.85 | L3MBTL1 (0.62) | KMT2AALDH1A1L3MBTL1RAB9ATDP1 | |
| SCHEMBL9853798 | 0.83 | TDP1 (0.54) | KMT2AMAPTL3MBTL1RAB9ATDP1 | |
| SCHEMBL9853819 | 0.81 | KDM4E (0.56) | KMT2AALDH1A1MAPTMEN1L3MBTL1 | |
| SCHEMBL9853829 | 0.80 | LMNA (0.45) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9853795 | 0.79 | ALDH1A1 (0.57) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL9853808 | 0.78 | ALDH1A1 (0.56) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| SCHEMBL1367920 | 0.78 | TDP1 (0.58) | KMT2AALDH1A1MAPTMEN1L3MBTL1 | |
| SCHEMBL17047599 | 0.77 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTMEN1L3MBTL1 | |
| SCHEMBL4910090 | 0.77 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |