Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872871 | 0.86 | AGTR2 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL9854231 | 0.82 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL1891328 | 0.81 | AGTR1 (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL8559933 | 0.80 | AGTR2 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL8958862 | 0.79 | AGTR2 (0.51) | AGTR1AGTR2 | |
| SCHEMBL1890240 | 0.79 | MAPK14 (0.42) | AGTR1AGTR2PPARG | |
| SCHEMBL13341068 | 0.78 | AGTR1 (0.42) | AGTR1AGTR2PPARG | |
| SCHEMBL2848776 | 0.78 | PPARG (0.41) | AGTR1AGTR2PPARG | |
| SCHEMBL4011357 | 0.77 | AGTR1 (0.40) | AGTR1AGTR2PPARG | |
| SCHEMBL9042199 | 0.77 | AGTR1 (0.35) | AGTR1AGTR2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |