SCHEMBL8958862

SCHEMBL8958862

CCCCc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2)c(C#N)c1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 3/20 0.51
AGTR1 P30556 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847866 0.94 AGTR2 (0.56) AGTR2AGTR1
SCHEMBL8872871 0.89 AGTR2 (0.59) AGTR2AGTR1
SCHEMBL9851425 0.85 AGTR1 (0.56) AGTR2AGTR1
SCHEMBL8559933 0.83 AGTR2 (0.66) AGTR2AGTR1
SCHEMBL9843965 0.80 CYP19A1 (0.46) AGTR2AGTR1
SCHEMBL7050680 0.80 AGTR1 (0.55) AGTR2AGTR1
SCHEMBL9854218 0.79 AGTR1 (0.44) AGTR2AGTR1
SCHEMBL8559553 0.79 AGTR1 (0.55) AGTR2AGTR1
SCHEMBL9443092 0.79 PPARG (0.68) AGTR2AGTR1
SCHEMBL9847780 0.78 PPARG (0.56) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559236-A Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists EISAI CO., LTD. (JP) 1996-09-24 US disclosed