Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12088954 | 0.83 | KDM4E (0.44) | MAPK1ALPLPARP1PARP3KDM4E | |
| SCHEMBL4047107 | 0.78 | PDE9A (0.35) | PDE9APDE1C | |
| SCHEMBL13905292 | 0.78 | PDE9A (0.35) | PDE9APDE1C | |
| SCHEMBL4124888 | 0.78 | DDAH1 (0.56) | MAPK1ALPLKDM4ETP53MAPT | |
| SCHEMBL4361327 | 0.75 | DDAH1 (0.55) | MAPK1KDM4ETP53ALDH1A1MAPT | |
| SCHEMBL31661032 | 0.75 | GRM4 (0.34) | KDM4EALDH1A1LMNA | |
| SCHEMBL31660973 | 0.75 | CYP1A2 (0.37) | MAPK1PARP1TP53MAPTPDE10A | |
| SCHEMBL7002587 | 0.74 | GAA (0.42) | MAPK1TP53ALDH1A1MAPTPKM | |
| SCHEMBL4523575 | 0.74 | DDAH1 (0.35) | MAPK1TP53ALDH1A1MAPTPKM | |
| SCHEMBL6948812 | 0.72 | PKM (0.58) | MAPK1TP53ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |