Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233304 | 0.84 | CYP1A2 (0.43) | DDAH1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL4361327 | 0.81 | DDAH1 (0.55) | DDAH1PKMALDH1A1AXLNUDT1 | |
| SCHEMBL7002587 | 0.80 | GAA (0.42) | DDAH1PKMALDH1A1AXLNUDT1 | |
| SCHEMBL6948812 | 0.78 | PKM (0.58) | DDAH1PKMALDH1A1AXLNUDT1 | |
| SCHEMBL9853629 | 0.78 | KDM4C (0.48) | DDAH1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18291869 | 0.77 | ALDH1A1 (0.38) | DDAH1PKMRIPK1ALDH1A1AXL | |
| SCHEMBL5264712 | 0.77 | ALDH1A1 (0.38) | DDAH1PKMALDH1A1AXLNUDT1 | |
| SCHEMBL2972100 | 0.77 | ALDH1A1 (0.38) | DDAH1PKMRIPK1ALDH1A1AXL | |
| SCHEMBL8288254 | 0.77 | MAPT (0.40) | DDAH1PKMRIPK1ALDH1A1AXL | |
| SCHEMBL4347806 | 0.77 | RIPK1 (0.43) | RIPK1ALDH1A1AXLNUDT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318443-A1 | KINASE INHIBITORS | BONJOUKLIAN ROSANNE | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318443-A1 | KINASE INHIBITORS | MAP3K20, MAP3K19, MAP3K1 | DDAH1 1884/4885PKM 531/4885RIPK1 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.