Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854386 | 0.86 | PPARG (0.53) | BRD4PPARGLMNAAGTR1AGTR2 | |
| SCHEMBL8566073 | 0.84 | PPARG (0.61) | BRD4PPARGLMNARAB9ATP53 | |
| SCHEMBL9853637 | 0.82 | PPARG (0.74) | PPARGLMNATP53AGTR1AGTR2 | |
| SCHEMBL9854307 | 0.82 | PPARG (0.49) | BRD4PPARGLMNAAGTR1AGTR2 | |
| SCHEMBL9854355 | 0.81 | PPARG (0.53) | PPARGALDH1A1LMNAHPGDTP53 | |
| SCHEMBL8874596 | 0.81 | PPARG (0.53) | BRD4PPARGLMNATP53AGTR1 | |
| SCHEMBL9851543 | 0.81 | AGTR1 (0.66) | PPARGALDH1A1LMNAAGTR1AGTR2 | |
| SCHEMBL9854316 | 0.80 | PPARG (0.47) | PPARGALDH1A1LMNAHPGDTP53 | |
| SCHEMBL9854341 | 0.80 | PPARG (0.54) | PPARGALDH1A1LMNAHPGDTP53 | |
| SCHEMBL8874522 | 0.77 | MEN1 (0.53) | PPARGSMN1; SMN2LMNATP53AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |