Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854307 | 0.95 | PPARG (0.49) | PPARGAGTR1AGTR2RXFP1NOS1 | |
| SCHEMBL9854386 | 0.81 | PPARG (0.53) | PPARGAGTR1AGTR2LMNACNR2 | |
| SCHEMBL9854319 | 0.80 | BRD4 (0.53) | PPARGAGTR1AGTR2ALDH1A1HPGD | |
| SCHEMBL9854477 | 0.80 | AGTR1 (0.45) | AGTR1AGTR2RXFP1NOS1NOS2 | |
| SCHEMBL8566073 | 0.79 | PPARG (0.61) | PPARGAGTR1AGTR2LMNAENPP2 | |
| SCHEMBL8872236 | 0.79 | AGTR1 (0.69) | PPARGAGTR1AGTR2NOS1NOS2 | |
| SCHEMBL9853637 | 0.77 | PPARG (0.74) | PPARGAGTR1AGTR2LMNAENPP2 | |
| SCHEMBL9854341 | 0.77 | PPARG (0.54) | PPARGAGTR1AGTR2ALDH1A1HPGD | |
| SCHEMBL9854355 | 0.77 | PPARG (0.53) | PPARGAGTR1AGTR2RXFP1ALDH1A1 | |
| SCHEMBL8874596 | 0.77 | PPARG (0.53) | PPARGAGTR1AGTR2LMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |